Which health problems can congenital syphilis cause in infants who survive?

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Infants who survive congenital syphilis may be born with several health complications, including skin rashes, pneumonia, and skeletal abnormalities.1

If the condition remains untreated, it can lead to severe long-term health issues, such as:

In rare instances, an infant may appear healthy at birth, with no symptoms manifesting until adolescence, at which point signs of late-stage syphilis may emerge. Because these outcomes are preventable through timely medical intervention, it is a fundamental ethical imperative to ensure that pregnant women have access to proper screening and penicillin treatment, which effectively prevents the transmission of the infection to the fetus.12