Which body systems besides muscles can be affected by myotonic dystrophy?

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Myotonic dystrophy is a multisystem disorder, meaning it affects various parts of the body beyond the muscular system. In addition to muscle fiber degeneration, the condition is associated with the following systemic manifestations:

  • Endocrine system: Patients may experience endocrine deficiencies and gonadal atrophy.12
  • Gastrointestinal system: Dysfunction of the gastrointestinal tract is a common symptom.1
  • Integumentary system: Premature balding is frequently observed.12
  • Ocular system: The early formation of cataracts is a characteristic feature.12
  • Neurological/Cognitive: The disease can lead to mental impairment and cognitive degeneration.12
  • Cardiovascular system: Heart problems may also be present in affected individuals.2