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Which amino acids have polar uncharged side chains?
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Amino acid
The structure and function of amino acids.
The amino acids classified as having polar, uncharged side chains are serine, cysteine, threonine, tyrosine, asparagine, and glutamine.1
These amino acids are characterized by side chains containing atoms such as nitrogen, oxygen, or sulfur, which provide electron pairs that facilitate hydrogen bonding with water and other molecules.1
Specific structural features within this group include:
* Hydroxyl groups: Serine, threonine, and tyrosine contain hydroxyl groups, which are sites for phosphorylation.1
* Sulfur: Cysteine contains a chemically reactive sulfur atom.1
* Amide groups: Asparagine and glutamine possess amide R groups, where the carbonyl group acts as a hydrogen bond acceptor and the amino group acts as a hydrogen bond donor.1