What percentage of human blood is made up of red blood cells?

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The percentage of human blood volume occupied by red blood cells is measured by a diagnostic procedure called a hematocrit. This value varies based on sex and age.21

In healthy adults, the volume of packed red blood cells typically falls within the following ranges:

  • Men: Approximately 42 to 54 percent2
  • Women: Approximately 37 to 47 percent2

These values are generally lower in children. An abnormal hematocrit—whether the percentage is too high or too low—can serve as an important clinical indicator of various health conditions, such as anemia or polycythemia.2341