What is the function of Bowmanâs capsule in a nephron?
Bowmanâs capsule is a double-walled, cuplike structure that serves as the initial filtration unit of the nephron within the kidney.12
Its primary function is to facilitate the filtration of blood. It encloses a cluster of microscopic capillaries known as the glomerulus, and together these structures form the renal corpuscle. During the filtration process, blood pressure forces plasmaâexcluding large molecules like proteinsâout of the glomerular capillaries and through the inner wall of the capsule.13
This resulting fluid, referred to as capsular urine, is then collected by the capsule and passed into the nephron tubule for further processing, where it is eventually modified into urine through the secretion of substances and the selective reabsorption of water and other constituents. In conditions such as glomerulonephritis, the normal function of these structures can be severely compromised by inflammation.324