What does the activated partial thromboplastin time test help detect?

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The activated partial thromboplastin time (APTT) test is a laboratory procedure used to assess the activity of the intrinsic pathway of blood coagulation.1

By measuring the time it takes for a plasma sample to form a visible clot after the addition of specific reagents, the test helps detect potential coagulation disorders. Specifically, a prolonged APTT result may indicate:12

  • A deficiency in the activity of one or more blood-clotting factors.1
  • The presence of a chemical inhibitor of blood coagulation.1

This test is a key screening tool for identifying bleeding disorders, particularly when a patient exhibits symptoms such as delayed wound clotting or unexplained hemorrhages.2