What does luteinizing hormone do during the menstrual cycle?

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Luteinizing hormone (LH) is a gonadotropic hormone produced by the pituitary gland that plays a critical role in the female reproductive cycle. Its primary functions during the menstrual cycle include:1

  • Triggering Ovulation: A sudden peak release of LH from the pituitary gland stimulates the release of an egg from the ovary, an event that typically occurs around the middle of the monthly cycle.23
  • Formation of the Corpus Luteum: Following ovulation, LH promotes the transformation of the ruptured ovarian follicle into the corpus luteum.13
  • Hormone Secretion: The resulting corpus luteum acts as an endocrine gland that secretes progesterone and estrogens. Progesterone is essential for preparing the uterus for the potential implantation of a fertilized egg.143

If fertilization does not occur, the corpus luteum becomes inactive, leading to a drop in hormone levels and the onset of menstruation.43