What can trigger sleepwalking and other NREM parasomnias?
NREM parasomnias, which include sleepwalking and sleep terrors, are disruptive sleep-related disorders that typically occur during the deepest stage of NREM sleep (N3). These episodes are characterized by EEG patterns that reflect a mix of sleep and wakeful states, leaving the individual generally unresponsive to external stimuli and often without memory of the event.12
Several factors can trigger these parasomnias, including:
- Sleep deprivation or fragmented sleep1
- Stress1
- Fever1
- Alcohol consumption1
- Medications1
Additionally, some individuals may have a genetic predisposition to these disorders. Research into sleepwalking, for instance, suggests it often runs in families, with studies identifying potential links to specific regions of chromosome 20. While the exact mechanisms are not fully understood, these triggers likely disrupt the stability of the sleep cycle, leading to the partial arousals that define NREM parasomnias.13