Britannica Sources used in this answer

What are the three tissue layers of the uterus?

Created from Britannica articles using AI. AI can make mistakes, so verify using Britannica articles.

The uterus is composed of three distinct tissue layers:1

  • Perimetrium (Serous coat): The outermost layer, which consists of a serous membrane of peritoneum that partially covers the organ.1
  • Myometrium: The middle layer, which is the thickest and comprises the bulk of the uterine wall. It is composed of firm, densely packed smooth muscle fibers arranged in longitudinal, circular, and oblique directions.12
  • Endometrium: The innermost layer, which is a mucous membrane that lines the uterine cavity. This layer contains numerous glands and blood vessels and undergoes significant cyclical changes throughout a person's reproductive life.12