Britannica Sources used in this answer

How long does treatment for localized leprosy usually last?

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For patients diagnosed with localized forms of leprosy, where there are relatively few leprosy bacilli present in the body, the standard treatment duration is six months.1

This regimen utilizes multidrug therapy, which involves the combination of two specific medications: dapsone and rifampicin. This approach is highly effective at halting the progression of the disease and preventing the development of drug-resistant strains.1