How does the hydrogen phosphate ion act as an acid or a base?

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Under the Brønsted–Lowry definition, an acid is a species that tends to lose a proton (H+), while a base is a species that tends to gain one. The hydrogen phosphate ion (HPO42−) is considered amphoteric, meaning it can function as either an acid or a base depending on the chemical environment.1

It acts as an acid by losing a proton to form the phosphate ion, and it acts as a base by accepting a proton to form the dihydrogen phosphate ion. These processes are represented by the following equations:1

  • As an acid: HPO42−⇌PO43−+H+1
  • As a base: HPO42−+H+⇌H2PO4−1

Because it can participate in both reactions, the hydrogen phosphate ion is a versatile species in acid–base chemistry, capable of adjusting its role to maintain equilibrium in a system.1