How does systemic lupus erythematosus affect Black women differently from white women?

Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder that disproportionately affects women, particularly those between the ages of 12 and 40.12

Regarding the prevalence of the disease among different populations, research indicates that systemic lupus erythematosus is three times more common in Black women than in white women. While the disease is generally more common in Black and some Asian populations, the underlying reasons for these disparities—and the specific ways the disease may manifest differently between these groups—remain a subject of ongoing study within the context of connective tissue disease.21

Regardless of demographic background, the condition is characterized by a breakdown of the immune system, leading to the production of autoantibodies that cause chronic inflammation and potential damage to various organs, including the skin, kidneys, joints, and nervous system.12