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How does rickets affect the shape and strength of children’s bones?

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bone disease Defect of tibia, caused by septic osteomyelitis in childhood, with compensatory thickening of the fibula (right). Normal bones are shown at left.

Rickets is a disease of infancy and childhood characterized by the softening of bones due to inadequate mineralization, typically caused by a lack of vitamin D.12

Impact on Bone Strength

Vitamin D is essential for the body to absorb calcium and phosphate, which are deposited into the protein matrix of bone to provide rigidity. In the absence of sufficient vitamin D, this matrix remains poorly calcified, resulting in bones that are soft and weak.1

Impact on Bone Shape and Growth

Because these softened bones are pliable, they are prone to curving and abnormal growth. Common skeletal deformities and growth-related issues include:1
* Curvature: Children may develop bowlegs or knock-knees.12
* Enlargement: There is often an overgrowth of cartilage, leading to enlarged ends of long bones and a "rachitic rosary" at the junction of the ribs and chest.1
* Stunted Growth: The disease can lead to short stature and a bulging forehead.1
* Structural Changes: A narrowed chest and pelvis can occur, which may cause health complications later in life.1