Britannica
Sources used in this answer
How does autolysis begin the decomposition of a body?
Created from Britannica articles
using AI.
AI can make mistakes, so verify using Britannica articles.
death
Learn what happens to the body after death.
Autolysis, often referred to as self-digestion, is the process that initiates the decomposition of a body following death.1
It begins when cells become oxygen-deprived, causing internal enzymes to begin digesting the cells' own membranes. A key component in this process is the lysosome, a subcellular organelle that normally houses hydrolytic enzymes responsible for breaking down macromolecules. In a living cell, these enzymes are contained within a membrane to prevent self-degradation; however, upon death, the dissolution or rupture of these lysosomes releases the enzymes into the intracellular environment. This leads to the breakdown of cellular structures and the beginning of tissue decomposition.123