How does an electrical impulse travel through the heart’s conduction system?

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The heart’s rhythmic contraction is governed by an internal conduction system that ensures the coordinated pumping of blood. This process begins in the sinoatrial (SA) node, a cluster of specialized pacemaker cells located in the right atrium.12

These cells possess the unique ability to spontaneously depolarize, generating an electrical impulse that sets the heart's pace. The signal travels through the heart via the following pathway:23

  • Atrial Propagation: The impulse spreads from the SA node across the atria, causing them to contract.13
  • Atrioventricular (AV) Node: The signal reaches the AV node, which acts as a relay point.23
  • Ventricular Conduction: From the AV node, the impulse is transmitted rapidly through the bundles of His and the Purkinje system.23
  • Ventricular Contraction: The signal disperses into the ventricular muscle cells, triggering a coordinated contraction that pumps blood to the lungs and the rest of the body.13

This propagation is facilitated by low-resistance pathways between cells, such as intercalated disks, and is driven by the movement of ions like sodium, potassium, and calcium across cell membranes.23