How does a white blood cell differential measure the different types of white blood cells?

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A white blood cell differential is a laboratory test that measures the percentage of each specific type of white blood cell present in a sample, typically calculated per 100 white cells counted.12

This analysis identifies the proportions of the following cell types:
* Neutrophils (including both band and segmented forms)2
* Lymphocytes2
* Monocytes2
* Eosinophils2
* Basophils2

By determining the relative distribution of these cells, clinicians can gain insight into a patient's health status. For instance, abnormal values in specific cell types can help identify the nature of an infection or disease; viral infections often impact lymphocyte counts, while bacterial infections may increase the percentage of band neutrophils. Similarly, elevated eosinophils are frequently associated with allergic conditions or parasitic infections. This test is often performed in conjunction with a complete blood count to provide a comprehensive overview of an individual's hematologic parameters.21