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How do trans fats affect HDL cholesterol levels?

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Trans fats negatively impact cardiovascular health by lowering levels of high-density lipoprotein (HDL) cholesterol.1

HDL cholesterol is considered "good" cholesterol because it plays a vital role in transporting cholesterol from cells and blood vessels to the liver for metabolism and excretion. Because HDL levels are inversely correlated with the risk of heart disease, the depletion of HDL caused by the consumption of trans fats increases the risk of cardiovascular disease.12

In addition to lowering HDL, trans fats also raise levels of low-density lipoprotein (LDL) cholesterol, creating a dual negative effect on cholesterol profiles.12