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How do infected mosquitoes transmit Plasmodium parasites to humans?

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Infected female Anopheles mosquitoes transmit Plasmodium parasites to humans during a blood meal.12

When an infected mosquito bites a human, it injects immature forms of the parasite, known as sporozoites, into the host's bloodstream via its saliva. Once inside the human body, these parasites are transported to the liver, where they mature and multiply. Following this stage, the parasites reenter the bloodstream to invade and destroy red blood cells, which leads to the characteristic symptoms of malaria.12