How do fluke parasites renew their outer integument inside a host?

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Fluke parasites renew their outer integument through the continuous release of secretory bodies contained within the outer part of the tissue. These bodies are released at the surface to renew the apical membrane, a process that serves as a protective mechanism against the host's immune response.1

Unlike free-living flatworms, which possess an epidermis of ciliated cells, the tegument of flukes is a metabolically active syncytiumβ€”a layer of cells not separated by cell walls. This specialized structure, which often features spines and sensory papillae, allows the parasite to maintain its integrity while residing within the challenging environment of a host.21