How do Plasmodium parasites multiply inside liver cells?

When Plasmodium parasites enter the human body via the bite of an infected Anopheles mosquito, the immature forms, known as sporozoites, travel through the bloodstream to the liver.21

Inside the liver parenchyma cells, the sporozoites mature into forms called schizonts. These schizonts undergo a process of asexual multiple division known as schizogony. During this stage, which typically lasts one to two weeks, each schizont multiplies to produce thousands of individual parasites called merozoites. Once this process is complete, the liver cells rupture, releasing the merozoites into the bloodstream to begin the next phase of the infection by invading red blood cells.132