How can ischemic heart disease lead to angina or a heart attack?
Ischemic heart disease, also known as coronary heart disease, occurs when atherosclerosis causes fatty plaques to build up in the coronary arteries, restricting blood flow to the heart muscle.12
Angina Pectoris
Angina pectoris arises when these narrowed arteries cannot deliver sufficient oxygen-rich blood to meet the heart's metabolic demands, particularly during physical exertion or emotional stress. This temporary imbalance causes waste products to accumulate in the muscle, irritating nerve endings and resulting in chest discomfort, often described as a squeezing or heavy sensation. These symptoms typically subside with rest or medication.34
Heart Attack
A heart attack (myocardial infarction) occurs when blood flow is abruptly and severely interrupted. This most commonly happens when an atherosclerotic plaque ruptures, triggering the formation of a blood clot that completely blocks a coronary artery. Without oxygen, the affected segment of the heart muscle begins to die (necrosis), leading to prolonged, intense pain that does not resolve with rest. Immediate medical intervention is essential to restore circulation and minimize permanent damage.215