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How can epididymitis lead to sterility?

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varicocele — reproductive system disease Varicocele, enlargement of the veins of the spermatic cord, is a cause of infertility in men.

Epididymitis is the inflammation of the epididymis, the coiled ductal structure responsible for the maturation, nourishment, and storage of sperm.123

This condition can lead to sterility primarily because the inflammation may cause physical blockages within the genital tract. Because the epididymis consists of narrow, tightly coiled channels, inflammatory processes can result in the formation of adhesions or obstructive growths that close these tubal pathways. When these ducts are blocked, sperm are prevented from moving through the genital tract, effectively obstructing their transport during ejaculation.423

If left untreated, severe or chronic inflammation may permanently damage these delicate structures, hindering the body's ability to transport sperm and resulting in infertility. It is essential that such infections are addressed promptly with appropriate antibiotics to prevent long-term complications.12