How are trans fats associated with type 2 diabetes?

Trans fats are associated with an increased risk of developing type 2 diabetes mellitus. While the primary health concerns regarding trans fats have historically focused on their negative impact on cardiovascular health—specifically their ability to raise LDL cholesterol and lower HDL cholesterol—research has also identified a link between their consumption and the onset of this metabolic condition.12

It is important to note that while trans fats are a significant dietary concern, the relationship between diet and diabetes is multifaceted. For instance, high-carbohydrate diets can also increase cardiovascular risk for individuals who are already prone to metabolic syndrome or type 2 diabetes. Because of the established health risks associated with manufactured trans fats, many health organizations and governments have implemented regulations to limit their use in food products, and physicians generally recommend avoiding them entirely.21