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Who is the primary antagonist of Avengers: Endgame?

The primary antagonist of Avengers: Endgame is Thanos, the Mad Titan. The Avengers initially hunt down Thanos but learn that he destroyed the infinity stones to ensure his actions could not be reversed. Later a past Thanos is transported to the present to retrieve the stones and wipe out the universe entirely before rebuilding it from scratch as he sees fit.