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Who contributed to the early understanding of probiotics?

Élie Metchnikoff, a Russian-born zoologist and microbiologist, is often credited with introducing the idea that the ingestion of certain kinds of microorganisms can benefit digestion as well as immune function. Metchnikoff’s idea emerged in the early 20th century. Investigation of the potential health applications of probiotics gained interest in the early 21st century, as research into the human microbiome expanded.