Dependence occurs when the body adapts to repeated drug exposure and withdrawal symptoms develop if use is reduced or stopped. Tolerance occurs when the body becomes less responsive to a drug, so a larger dose may be needed to produce the same effect. The two can occur together, but one does not necessarily imply the other.
verifiedCite
While every effort has been made to follow citation style rules, there may be some discrepancies.
Please refer to the appropriate style manual or other sources if you have any questions.
Select Citation Style