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How does heroin addiction develop?

Heroin addiction develops because the drug alters brain chemistry, primarily by affecting the neurotransmitter dopamine, which plays a central role in the brain’s reward system. These alterations in dopamine serve to reinforce reward pathways, fueling repeated use of the drug. The consequent changes in brain circuitry significantly affect decision-making and impulse control, giving rise to compulsive drug-seeking behavior and continued drug use. Compulsive use occurs despite negative consequences.