The loss of territory discredited Mexico’s conservative government, and it resulted in uncertainty among Mexicans about the country’s future as an independent state. The Mexican Cession and the Gadsden Purchase (1853) contributed to the outbreak of La Reforma, a civil war between liberals and conservatives that began in 1854 and continued until 1876, as well as to the fall of Antonio López de Santa Anna as leader of Mexico in 1855.
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