Type 1 diabetes mellitus usually develops in childhood and is commonly caused by autoimmune destruction of structures known as the islets of Langerhans in the pancreas. The islets of Langerhans house insulin-producing beta cells. Type 1 diabetes accounts for about 5 to 10 percent of diabetes cases. Type 2 diabetes mellitus accounts for about 90 percent of cases and is strongly associated with obesity, insulin resistance, and insulin deficiency. It most often occurs in adults, though it can also occur in children and adolescents.
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