chlorpheniramine
chlorpheniramine, synthetic drug used to counteract the histamine reaction, as in allergies. Chlorpheniramine, introduced into medicine in 1951, is administered orally or by intravenous, intramuscular, or subcutaneous injection in the form of chlorpheniramine maleate. It is effective in controlling the symptoms of hay fever, acute skin reactions (such as hives), and contact dermatitis (such as from poison ivy). The most common side effect is drowsiness, although dryness of the mouth, difficulty in urinating, and vision problems also may occur.
This article was most recently revised and updated by Amy Tikkanen.
Citation Information
Article Title:
chlorpheniramine
Website Name:
Encyclopaedia Britannica
Publisher:
Encyclopaedia Britannica, Inc.
Date Published:
08 September 2026
Access Date:
November 14, 2026