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Which roads form the main west-to-east routes through central Karachi?

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The central layout of Karachi is defined by four major arterial roads that run in a parallel west-to-east alignment through the city center, beginning near the port at Mereweather Tower.1

These primary routes are:

Nishter Road (formerly Lawrence Road)1
Mohammed Ali Jinnah Road (formerly Bandar Road)1
Shahrah-e-Liaquat (formerly Frere Road)1
I.I. Chundrigar Road (formerly McCleod Road)1

These roads serve as the core framework for the city's central district, with commercial and government functions concentrated along them. While these arteries facilitate west-to-east movement, other thoroughfares such as Napier Road, Dr. Zia-ud-din Ahmed Road, and Garden Road intersect them perpendicularly to provide north-to-south connectivity.1