Which major cities lie along or near the Rio Grande in the United States?

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Several major cities in the United States are located along or near the Rio Grande. These urban centers play significant roles in the economy and history of the region.1

In New Mexico, the major cities situated along the river include:
* Albuquerque
* Las Cruces

In Texas, the major cities located along or near the Rio Grande include:
* El Paso
* Del Rio
* Laredo
* Brownsville

These cities are part of a basin that has supported human settlement and irrigation since prehistoric times, and they remain vital hubs for agriculture, industry, and international trade today.12