Which cities are among the largest urban centers of the Great Plains?

Although the Great Plains region is characterized by a sparse rural population, approximately three-fifths of its residents live in urban areas. While there are relatively few large cities, several urban centers serve as significant hubs for the region.1

The largest cities in the Great Plains include:

• Edmonton and Calgary in Alberta, Canada1
• Denver, Colorado, which serves as a major transportation, industrial, and commercial hub for the region12

Other notable cities within the Great Plains include:

• Oklahoma City, Oklahoma1
• Saskatoon and Regina in Saskatchewan, Canada1
• Amarillo, Lubbock, and Odessa in Texas1

These cities often function as essential service centers for the surrounding agricultural and ranching communities, helping to concentrate economic and social activities in a region defined by its vast, open landscapes.1