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Britannica Sources used in this answer

Where was the ancient region of Persis located?

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Map showing the extent of the Achaemenid Empire during the 6th and 5th centuries BC, shaded in light green and spanning from the eastern Mediterranean and Egypt through the Middle East to parts of Central Asia and the Indus Valley. Major regions, cities, and trade routes such as the Royal Road are labeled within the empire's boundaries.
ancient Iran

The ancient region of Persis was located in the southwestern part of Iran, a territory roughly coextensive with the modern-day region of Fars.12

As the ancestral homeland of the Achaemenian dynasty, the area held significant political and cultural importance. It served as the site for major royal capitals, including Pasargadae, established by Cyrus the Great, and Persepolis, which was founded by Darius I approximately 30 miles (48 km) to the southwest of Pasargadae.13