How is the Sierra Mixteca connected to the Sierra Madre del Sur?

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The Sierra Mixteca serves as a highland bridge that connects the Cordillera Neo-Volcánica to the Southern Highlands, which constitute the core of the Sierra Madre del Sur.1

While the Sierra Madre del Sur is bounded to the north by the structural depression of the Balsas River, the Sierra Mixteca is situated to the east of this depression, effectively linking these major physiographic regions.1