How did Urbain-Jean-Joseph Le Verrier predict Neptune’s location?

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Urbain-Jean-Joseph Le Verrier predicted the location of Neptune by mathematically analyzing the irregular orbit of Uranus.1

Astronomers had observed that Uranus was not following the path predicted by Newton’s laws of motion and the gravitational influence of the known planets. Le Verrier hypothesized that these orbital perturbations were caused by the gravitational pull of an undiscovered planet.21

In 1845, he began a study to calculate the size and position of this unknown body. By mid-1846, he had successfully computed its probable location. He communicated these results to the German astronomer Johann Gottfried Galle at the Berlin Observatory, who, with the help of detailed star maps, identified the planet on September 23, 1846, within one degree of the position Le Verrier had calculated.123