islets of Langerhans: Quick Facts

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Facts

Also Known As	pancreatic islets • islands of Langerhans

Photos

An anatomical illustration of the human pancreas shows its location near the stomach and intestines, a detailed cross-section highlighting ducts and the islet of Langerhans, and an inset of pancreatic tissue histology with labeled alpha, beta, and delta cells.

Diagram showing a cross-section of a pancreatic islet of Langerhans on the left, with alpha, beta, and delta cells labeled by color, and on the right, arrows illustrating paracrine interactions among these cell types through hormones glucagon, insulin, and somatostatin.

Ball-and-stick molecular model of insulin, with clusters of multicolored spheres representing atoms, connected and outlined in yellow against a dark background.

Major glands of the human endocrine system. The hypothalamus stimulates the pituitary gland and influences food intake, weight regulation, fluid intake and balance, thirst, body heat, and the sleep cycle. Pituitary hormones stimulate growth, egg and sperm development, milk secretion, and release of hormones by other glands. The pineal gland may play a significant role in sexual maturation and the circadian rhythm. Thyroid hormones regulate the metabolic rate of tissues, stimulate the contraction of heart muscle, and are necessary for normal growth and brain development before birth and during infancy. Parathyroid hormone regulates calcium, phosphorus, and magnesium levels. The adrenal glands regulate salt and water retention, some reactions of the immune system, and blood pressure. The islets of Langerhans regulate blood sugar levels. The ovaries and testes produce hormones that regulate the reproductive system and that produce male and female secondary sex characteristics.

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Topics

alpha cell beta cell delta cell Insulin somatostatin Glucagon pancreatic polypeptide pancreas

Key People

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Eugene Lindsay Opie

American pathologist

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