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G protein-coupled receptor: Quick Facts

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Rebalancing the body's cellular communication system could slow aging • Oct. 22, 2026, 5:00 AM ET (Medical Xpress)

Facts

Also Known As heptahelical receptor • GPCR • seven-transmembrane receptor

Photos

Diagram showing how epinephrine binding to a beta-adrenergic receptor on a cell membrane activates a G-protein, which then stimulates adenylyl cyclase to convert ATP into cyclic AMP (cAMP), leading to physiological effects such as increased heart rate, blood vessel dilation, and glycogen breakdown.
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Key People

Robert J. Lefkowitz.
Robert J. Lefkowitz
American physician and biologist
Brian K. Kobilka, 2012.
Brian K. Kobilka
American physician and biologist