Why was the site of San Carlo alle Quattro Fontane difficult to build on?

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The site of San Carlo alle Quattro Fontane was considered difficult to build on because it was extremely cramped and narrow.12

Architect Francesco Borromini was tasked with fitting a complex, influential Baroque church into this restricted space, which was no larger than the dimensions of a single pier at St. Peter’s Basilica. To overcome these spatial limitations, Borromini utilized an unusual, irregular floor plan based on a Greek cross defined by convex curves and employed innovative geometric configurations to integrate the structure’s various elements, including its dome.132