Why did Ivan Pavlov’s theories about psychosis later receive criticism?

Ivan Pavlov’s theories regarding psychosis faced criticism primarily because he uncritically accepted existing psychiatric views on conditions like schizophrenia and paranoia while attempting to apply his physiological laws to them.1

Specifically, Pavlov assumed that the excessive inhibition observed in psychotic patients functioned as a protective mechanism to exclude injurious stimuli. Many contemporary psychiatrists consider these explanations too limited to account for complex mental phenomena. Furthermore, his reliance on neural concepts such as induction and irradiation to explain higher mental activity has been superseded in modern science by advancements in fields like electrophysiology and biochemistry.21