Why did Isabella of France leave England for France in 1325?

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Edward III Edward III, watercolour, 15th century; in the British Library (Cotton MS. Julius E. IV).

Isabella of France traveled to France in 1325 primarily to resolve a long-standing diplomatic dispute regarding Gascony.1

While the mission was intended to address these territorial tensions, it also served as a turning point in her relationship with her husband, Edward II. Once in France, she was joined by her son, the future Edward III, and subsequently refused to return to England until the Despensers—the king's favorites whom she strongly opposed—were removed from the royal court.1