Who became Muhammad’s guardian after the deaths of his mother and grandfather?

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Medina, Saudi Arabia: Prophet's Mosque — Muhammad The Prophet's Mosque, showing the green dome built above the tomb of Muhammad, Medina, Saudi Arabia.

After the death of his mother, Āminah, when he was six years old, and the death of his grandfather, ‘Abd al-Muṭṭalib, when he was eight, Muhammad’s guardianship was assumed by his uncle, Abū Ṭālib, who was the new head of the clan of Hāshim.1