Which ship in Ferdinand Magellan’s fleet was wrecked near the Santa Cruz River?

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The ship in Ferdinand Magellan’s fleet that was wrecked near the Santa Cruz River was the Santiago.1

The vessel had been surveying the area prior to the fleet's arrival at the river's mouth. The loss of the Santiago, combined with the later desertion of the San Antonio, left Magellan with three ships to continue the expedition toward the Pacific Ocean.12