When did Thomas Henry Huxley coin the word “agnostic”?

The British biologist Thomas Henry Huxley first publicly coined the word "agnostic" in 1869. He introduced the term during a meeting of the Metaphysical Society in London to serve as a label for his own philosophical position.1

Huxley chose the term as an antithesis to the "Gnostic" figures of Church history, who claimed to possess extensive knowledge about the very subjects regarding which he felt ignorant. He described his agnosticism not as a creed, but as a method rooted in the rigorous application of reason, emphasizing the importance of recognizing the limits of one's knowledge.12