What hardships did Dmitri Mendeleev face during his childhood in Tobolsk?

Dmitri Mendeleev’s childhood in Tobolsk was marked by significant financial and personal instability. Born into a large family, he faced the following hardships:

• Father’s Blindness: His father, Ivan Pavlovich Mendeleev, lost his sight in 1834, the same year Dmitri was born.12
• Loss of a Parent: His father passed away in 1847, leaving the family without his support.12
• Economic Instability: To provide for the family, his mother, Mariya Dmitriyevna Kornileva, took over the operation of a small glass factory. This source of income was destroyed when the factory burned down in December 1848.12

Following these events, his mother moved him to St. Petersburg to pursue his education, though she passed away shortly after his enrollment at the Main Pedagogical Institute.1