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What enormous-number problem did Archimedes explore in The Sand-Reckoner?

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In his treatise The Sand-Reckoner, Archimedes explored the problem of calculating the number of grains of sand required to fill the entire universe.

To solve this, he had to overcome the limitations of the existing Greek numerical notation system. He achieved this by creating an original place-value system that utilized a base of 100,000,000, allowing him to express and manipulate such an enormous quantity.1