How far did Thutmose III's empire extend into Syria?

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Thutmose III significantly expanded the Egyptian empire into Syria, ultimately reaching the Euphrates River during his military campaigns.123

Following his initial victory at Megiddo, Egyptian control initially extended northward to a line connecting Byblos and Damascus. In his later, more audacious campaigns, he pushed further into the region, eventually crossing the Euphrates to confront the kingdom of Mitanni. The king marked this achievement by erecting a commemorative inscription on the eastern bank of the river, next to one previously placed by his grandfather, Thutmose I; this site represented the farthest point of his advance.21

Throughout these efforts, Thutmose III consolidated his influence by establishing supply bases along the Phoenician coast and installing local rulers as vassals to maintain order within his Asian territories.12