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How did the epidemics of the late 1570s affect Giovanni Pierluigi da Palestrina's family?

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The epidemics that swept through central Italy in the late 1570s had a devastating impact on the family of Giovanni Pierluigi da Palestrina. The outbreaks claimed the lives of his wife, Lucrezia Gori, and his two elder sons, Rodolfo and Angelo, both of whom had demonstrated significant musical promise. Palestrina himself also fell seriously ill during this period.1