How did the Massacre of Vassy help begin the French Wars of Religion?

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The Massacre of Vassy in March 1562 served as the immediate catalyst for the French Wars of Religion, a series of conflicts between Protestants and Roman Catholics that lasted until 1598.12

Following the death of King Francis II, Catherine de’ Medici, acting as regent for her son Charles IX, attempted to foster religious reconciliation. She moved away from the repressive policies of her predecessors and issued the Edict of January in 1562, which granted Huguenots a degree of legal toleration.13

This policy of moderation provoked a violent backlash from devout Catholics, led by the powerful house of Guise. When partisans of FranƧois, 2e duc de Guise massacred a Huguenot congregation at Vassy, it shattered the fragile peace. The event triggered widespread uprisings in the provinces, forcing the crown into a position where it could no longer protect its Protestant subjects through law, thereby plunging the nation into civil war.14532