How did Titano the Super-Ape weaken Superman?

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Heath Ledger as the Joker sits at an interrogation table with Christian Bale as Batman standing behind him in a scene from the film The Dark Knight. — Supervillain Heath Ledger (seated) as the Joker and Christian Bale as Batman in *The Dark Knight* (2008).

Titano the Super-Ape, a fictional character often depicted as a giant ape, weakens Superman by utilizing kryptonite.

While Superman is capable of physically touching the substance, it emits radiation that severely compromises his strength and vitality. This vulnerability is a common tactic employed by his adversaries, as the radiation specifically affects those born on the planet Krypton.1